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Tanya K. Murphy

Tanya K. Murphy, M.D.

Associate Professor

Dr. Tanya Murphy

After graduating Cum Laude from Florida State University, Dr. Murphy completed medical school, a psychiatric residency, and graduate training in child psychiatry at the University of Florida as well as completing the APPCI graduate program. She joined the Faculty of the Department of Psychiatry at the University of Florida in 1994. She is board certified in child and adolescent psychiatry, general psychiatry and has a Masters degree in Clinical Investigation. She is currently Division Chief of Child and Adolescent Psychiatry. In addition Dr. Murphy is the director of the University of Florida's Child Clinic for Anxiety, Tic and Autism Spectrum Disorders and is actively involved in teaching psychiatry residents and medical students in the specialized areas of Obsessive Compulsive Disorder, various other anxiety disorders, tic disorders, Asperger’s Syndrome and Autism. She is conducting research in the areas of pediatric psychopharmacology and infection-related childhood neuropsychiatric illnesses.

Clinical Interests

Since joining the Department of Psychiatry Dr. Murphy has fulfilled the duties of Medical Director for Child Psychiatry Outpatient and Inpatient Services, Director of the University of Florida Child and Adolescent Outpatient Services, and Medical Director of UF’s Residential Treatment and Evaluation Unit for Autism. She currently serves as Division Chief of Child and Adolescent Psychiatry and is Director of the UF Child Clinic for Anxiety, Tic and Autism Spectrum Disorders Her areas of clinical interest include the specialized areas of Obsessive Compulsive Disorder, various other anxiety disorders, tic disorders and Autism Spectrum Disorders.

Research Interests and Scholarly Interests

Dr. Murphy's current research efforts are aimed at understanding the role of infections in the onset of childhood psychiatric disorders. The welding of modern immunological techniques with developmental neuropsychiatric disorders is fertile ground for study. The PANDAS construct is a fine example of a hypothesis driven disease model that includes consideration of both genetic vulnerability and environmental antecedents.

Dr. Murphy was awarded a recently completed NIMH K23 grant for 5 years, to study and research the Neuroimmunology of Pediatric Neuropsychiatric Disorders. She was a co-investigator for 4 years on an NIMH R01 for the Prospective Study of PANDAS and has taken over as Principal Investigator in the 5th year of this grant.  Co-PI on a State funded service grant given to the Center for Autism and Related Disabilities, Dr. Murphy also has considerable experience in clinical trials. In 1999, she was awarded a Senior Travel Award by the Anxiety Disorders of America Association. In 2001, she was nominated to the National Tourette Syndrome Association Medical Advisory Board and Regional Obsessive Compulsive Foundation Scientific Advisory Board. Since 2002, Dr. Murphy has served as a member of The Tourette Syndrome Practice Parameter Work Group. She also served as Guest Editor for CNS Spectrums' issue on Neuroimmunology and has been a reviewer for numerous scientific journals such as Biological Psychiatry, American Journal of Psychiatry, Journal of Neuroimmunology, Movement Disorders, American Journal of Medical Genetics, Molecular Psychiatry and Psychiatry Research. She is a member of the Society for Biological Psychiatry, Tourette Syndrome Association,  Obsessive Compulsive Foundation, American Academy of Child and Adolescent Psychiatry, Anxiety Disorders of America Association, Society for Neuroscience, International Society of Neuroimmunology, Movement Disorder Society and the Society of Professors of Child and Adolescent Psychiatry.

Educational Interests and Accomplishments

Dr. Murphy regularly provides clinical teaching to residents and medical students. For formal didactics, she has taught Third Year Medical Students on the subject of Childhood Psychiatric Disorders, Pediatric Psychopharmacology to Psychology Graduate students, PGY2 Residents (6-8) and Child Psychiatry Fellows. She has spent several hours teaching Child and Adolescent Development and Psychopathology to Child Psychiatry Fellows and Child and Adolescent Psychiatric Emergencies to PGY 1 and 2 Residents. She is the faculty instructor for graduate level courses on Neuroimmunology and Autoimmunity. Dr. Murphy has served as a research mentor for the University Scholar’s Program, the NIH Research Training for Minority Students, the High School Advanced Scientific Program, APPCI fellows and new faculty. She has also sat on various dissertation committees.

In 1999, Dr. Murphy was a recipient of an NIMH K30 Advanced Postgraduate Program in Clinical Investigation Dean's Award that provided salary support. Continuing to take classes in the Advanced Postgraduate Program in Clinical Investigation (APPCI) from July of 1999 to December 2002, Dr. Murphy has had the opportunity to take graduate level coursework in such areas as statistics, research ethics, immunology, microbiology, grant-writing, etc. and to perform research under the supervision of a mentor. In 2002, she completed a Master of Science in Clinical Investigation.

Leadership And Service

From 1990-1992, Dr. Murphy served as a member of the Residency Selection Committee for the Department of Psychiatry and from 1991-1993 as a member on the Graduate Education Committee. She also served on the Committee on the Family (92-94), Undergraduate Education Committee ('94-present), Faculty Compensation Committee (1996), and the Search Committee for Chairman of the Department of Psychiatry (1997-1998). She was a Residency Coordinator from 1993 to 1994. In addition, she was part of the Child and Adolescent Inpatient Restructuring Committee as well as a member of the Resident Education Psychopharmacology Group. She has been a Mental Illness Non-Discrimination Regional Co-Coordinator and been an active speaker to national, state, and local groups on immunologic-based childhood psychiatric disorders. Dr. Murphy has also served as a grant reviewer for the Obsessive Compulsive Foundation, National Institutes of Mental Health, the Tourette Syndrome Association, the Association of University Centers on Disabilities and the Israel Science Foundation. She served on the NIH Roundtable for Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcus in June 2000. In 2001, Dr. Murphy was named to the Medical Advisory Board of the National Tourette Syndrome Association.

Selected Publications (since 2000)

Murphy TK, Bengtson MA, Tan JY, Carbonell E, Levin GM. Selective serotonin reuptake inhibitors in the treatment of paediatric anxiety disorders: a review. Int Clin Psychopharmacol, 2000 Aug;15 Suppl 2:S47-63.

Murphy TK, Goodman WK, Ayoub, EM, Voeller KS. On defining Sydenham chorea: Where do we draw the line? Biol Psychiatry 2000, 47:851-857.

Murphy TK, Benson N, Zaytoun A, Yang M, Braylan R, Ayoub E, Goodman WK. Progress Toward Analysis Of D8/17 Binding to B Cells In Children With Obsessive Compulsive Disorder And/Or Chronic Tic Disorder. J Neuroimmunology, 2001; 120(1-2):146-51.

Murphy TK, Petitto J, Voeller KS, Goodman WK. Obsessive Compulsive Disorder: Is there an Association with Childhood Streptococcal Infections and Altered Immune Function? Seminars in Clin Neuropsychiatry, 2001; 6(4):266-276.

Murphy TK, Goodman WK. Neuropsychiatric Disorders: The Neuroimmunological Link? Editorial, CNS Spectrums, 2001; 6(5):378.

Nguyen M, Murphy T. Mirtazapine for Excessive Masturbation in an Adolescent with Autism. Letter to the Editor, J Am Acad Child Adolesc Psychiatry, 2001; 40(8):868.

Nguyen M, Murphy T. Olanzapine and hypertriglyceridemia. J Am Acad Child Adolesc Psychiatry, 2001; 40(2):133-7.

Murphy TK, Goodman WK. Genetics of childhood disorders: XXXIV. Autoimmune disorders, part 7: D8/17 reactivity as an immunologic marker of susceptibility to neuropsychiatric disorders? Development and Neurobiology Invited Column, J Am Acad Child dolesc Psychiatry, 2002; 41(1):98-100.

Murphy TK, Sajid M, Soto O, Shapira N, Edge P, Yang M, Lewis MH, Goodman WK. Detecting pediatric autoimmune neuropsychiatric disorders associated with streptococcus in children with obsessive-compulsive disorder and tics. Biol Psychiatry, 2004; 55(1):61-8.

Shapira NA, Ward HE, Mandoki M, Murphy TK, Yang MC, Blier P, Goodman WK. A double-blind, placebo-controlled trial of olanzapine addition in fluoxetine-refractory obsessive-compulsive disorder. Biol Psychiatry, 2004; 55(5):553-5.

Storch EA, Gerdes A, Atkins J, Geffken GR, Star J, Murphy T. Behavioral treatment of child with Pediatric Autoimmune Neuropsychiatric Disorder associated with Group A Streptococcal Infection. J Am Acad Child Adolesc Psychiatry, 2004, 43:510-511 .

Storch EA, Murphy TK, Geffken G, Soto O, Sajid M, Allen P, Roberti J, Killiany E, Goodman W. Further Psychometric Properties of the Tourette’s Disorder Scale – Parent Rated Version (TODS-PR). Child Psychiatry Hum Dev, 2004; 35(2):107-20.

Storch EA, Murphy TK, Geffken G, Soto O, Sajid M, Allen P, Roberti J, Killiany E, Goodman W. Psychometric evaluation of the Children's Yale-Brown Obsessive-Compulsive Scale. Psychiatry Res, 2004; 129(1):91-8.

Murphy TK, Husted DS. Autoimmunity in obsessive-compulsive disorder and tic disorders. Rev Bras Psiquiatr, 2004; 26(4):218-9.

Storch EA, Heidgerken AD, Adkins JW, Cole M, Murphy TK, Geffken GR. Peer victimization and the development of obsessive-compulsive disorder in adolescence. Depression and Anxiety, 2005; 21(1):41-44.

Storch EA, Murphy TK, Geffken GR, Bagner DM, Soto O, Sajid M, Allen P, Killiany EM, Goodman WK. Factor analytic study structure of the Children’s Yale-Brown Obsessive-Compulsive Scale. J Clin Child and Adoles Psychology, 2005; 34(2):312-319.

Storch EA, Shapira NA, Dimoulas E, Geffken GR, Murphy TK, Goodman WK. The Yale-Brown Obsessive Compulsive Scale: The dimensional structure revisited. Depression and Anxiety, 2005; 22(1):28-35.

Murphy TK, Bengtson MA, Soto O, Edge PJ, Sajid MW, Shapira N, Yang M. Case series on the use of aripiprazole for Tourette Syndrome. Internat’l J Neuropsychopharm, 2005; 8(3):489-90.; Epub 2005 Apr 28.

Lewin AB, Storch EA, Merlo LJ, Adkins JW, Murphy TK, Geffken GR. Intensive Cognitive Behavioral Therapy for Pediatric Obsessive Compulsive Disorder: A Treatment Protocol for Mental Health Providers. Psychological Services, 2005; 2:91-104.

Storch EA, Murphy TK, Geffken GR, Sajid M, Allen P, Roberti JW Goodman WK. Reliability and validity of the Yale Global Tic Severity Scale. Psychological Assessment, 2005; 17(4):486-491.

Negin B, Murphy TK. Priapism Associated with Addition of Oxcarbazepine to Aripiprazole and Lithium. J Am Acad Child Adolesc Psychiatry. 2005; 44(12):1223-1224.

Lewin AB, Storch EA, Adkins J, Murphy TK, Geffken GR. Current directions in pediatric obsessive-compulsive disorder. Pediatric Annals 2005; 34(2):128-134.

Merlo LJ., Storch EA, Murphy TK, Goodman WK, Geffken GR. Assessment of pediatric OCD: A critical review of current methodology. Child Psychiatry and Human Develop, 2005; 36(2):195-214.

Larson MJ, Storch EA, Murphy TK. What are the diagnostic and treatment implications for PANDAS: pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections? Curr Psychiatry, 2005; 4: 33-48.

Lewin A, Storch EA, Adkins J, Merlo L, Murphy TK, Goodman WK, Geffken GR. Update and review on pediatric obsessive-compulsive disorder. Psychiatric Annals, 2005; 35:745-751.

Larson MJ, Storch EA, Lewin AB, Geffken GR, Murphy TK, Goodman WK. Treatment of pediatric obsessive-compulsive disorder: A review. Curr Psychiatry Reviews, 2005; 1:281-292.

Goodman WK, Murphy TK, and Lazoritz M. Risk of Suicidality During Antidepressant Treatment of Children and Adolescents. Primary Psychiatry, 2006; 13(1):43-50.

Storch EA, Murphy TK, Adkins JW, Lewin AB, Geffken GR, Johns N, Jann, KE, Goodman WK. The Children’s Yale-Brown Obsessive Compulsive Scale: Psychometric Properties of Child- and Parent-Report Formats. J Anxiety Disorders, 2006; Feb 23 Epub ahead of print].

Scahill L, Erenberg G, Berlin CM Jr, Budman C, Coffey BJ, Jankovic J, Kiessling L, King RA, Kurlan R, Lang A, Mink J, Murphy T, Zinner S, Walkup J; Tourette Syndrome Association Medical Advisory Board: Practice Committee. Contemporary assessment and pharmacotherapy of Tourette syndrome. NeuroRx, 2006; 3(2):192-206.

Murphy TK, Sajid MW, Goodman WK. Immunology of OCD. Psychiatric Clinics No Amer, 2006; 29(2):445-469.

Murphy TK, Storch EA, Strawser MS. Case Report: Selective Serotonin Reuptake Inhibitor-Induced Behavioral Activation in the PANDAS Subtype. Primary Psychiatry, 2006; 13(8):87-89.

Husted DS, Shapira NA, Murphy TK, Mann GD, Ward HE, Goodman WK. Effect of Comorbid Tics on a clinically meaningful response to 8-week Open-Label Trial of Fluoxetine in OCD. J Psychiatric Res, 2006; 20 [Epub ahead of print]

Storch EA, Murphy TK, Bagner DM, Johns NB, Baumeister AL, Goodman WK, Geffken GR. Reliability and Validity of the Child Behavior Checklist Obsessive-Compulsive Scale. J Anxiety Disorders, 2006; 20(4):473-485. Epub 2005 Jul 25.

Goodman WK, Storch EA, Geffken GR, Murphy TK. Obsessive-Compulsive Disorder in Tourette’s Syndrome. J Child Neurology, 2006; 21(8):704-14.

Storch EA, Ledley DR, Lewin AB, Murphy TK, Johns NB, Goodman WK, Geffken GR. Peer Victimization in Children with Obsessive-Compulsive Disorder: Relations with symptoms of psychopathology Social-Psychological Adjustment. J Clin Child Adoles Psychology, 2006; 35(3):446-455.

Storch EA, Murphy TK, Geffken GR, Mann G, Adkins J, Merlo LJ, Duke D, Munson M, Swaine Z, Goodman WK. Cognitive-Behavioral Therapy for PANDAS Related Obsessive-Compulsive Disorder: Findings from a Preliminary Wait-List Controlled Open Trial. J Am Acad Child Adolesc Psychiatry, 2006; 45(10):1171-8.

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